Central Winston-Salem

The urban core of Winston-Salem encompassing downtown, the Innovation Quarter, Old Salem, and the surrounding historic neighborhoods. Downtown is anchored by the Arts District along Trade and Liberty streets, the Innovation Quarter biotech campus, and Wake Forest University's graduate programs. Historic neighborhoods like West End, Ardmore, Washington Park, and Reynolda surround the core with tree-lined streets and early 20th-century architecture. The US-52 freeway bisects the urban area north-south, while Salem Parkway (US-421) provides the primary east-west corridor. WSTA bus routes radiate from the Clark Campbell Transportation Center downtown.